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CBD and Sleep: Benefits of Combining CBD and Melatonin

According to the CDC, over 70 million Americans suffer from chronic sleep problems and “lack of sleep is associated with injuries, chronic diseases, mental illnesses, poor quality of life and well-being, increased health care costs, and lost work productivity.”​​​​​​​​

One third of American adults get less nightly sleep than the recommended seven-hour minimum (Centers for Disease Control and Prevention, 2016). If you are one of them, you know how sleep deprivation can lead to feeling suboptimal throughout the course of a day. Even worse, insufficient sleep has been linked to seven of the top 15 causes of death in the U.S. (Kumar Chattu et al., 2018). But did you also know that in the midst of this public health epidemic (Kumar Chattu et al., 2018), many Americans are turning to a remedy that is low on risk and high on restfulness?

That remedy is cannabidiol. CBD, for short, is a natural, non-toxic, and non-psychoactive cannabinoid. (The term “cannabinoid” refers to a chemical compound from the Cannabis sativa plant.) CBD interacts with the human endocannabinoid system, keeping the body healthy and the mind happy. However, when taken on its own or separate from THC—cannabis’s famously psychoactive cannabinoid—CBD is known to have a calming effect. You can learn more about how can Tikva solutions support health and wellness here.

In fact, research has found that CBD works synergistically with melatonin, a naturally occurring hormone that tells the body it is time to sleep. Melatonin is created in the pineal gland and helps regulate the sleep-wake cycle, which can be disrupted by factors from stress, insomnia, alcohol, or too much ambient light before bed (Piccirillo, 2007, Rupp, 2006, Jung, Y. & St. Louis, E.K., 2016). When melatonin is not created in the body, taking a supplement may assist in this biological function. While many companies sell CBD and Melatonin supplements separately we have created a combination of the two. Tikva’s CBD and Melatonin solution can be used to better your sleep. Research has also suggested that CBD may be therapeutic for sufferers of insomnia, REM sleep behavior disorders, and excessive sleepiness during the day (Babson, Sottile & Morabito, 2017).

While CBD alone can be beneficial for sleep, administering full-spectrum hemp oils that contain multiple cannabinoids promises even greater impact. Using a product containing the cannabinoid CBN, for example, has been shown to improve sleep (Breus, 2019). In contrast, pharmaceutical sleep aids may cause sleepwalking, habit formation, and daytime sleepiness, according to Harvard Medical School (2017). CBD has not been shown to have any of these adverse effects.

Tikva’s CBD + Melatonin tablets are specifically dosed to help you fall asleep, stay asleep, and wake up feeling refreshed in the morning. ​​​​​​​​Each tablet has 10mg of CBD and 3mg of melatonin. The National Sleep Foundation does not recommend more than 5mg of melatonin per dose to prevent grogginess, which is why we have kept the dose to 3mg of melatonin per tablet.

Typically, people are advised to begin CBD treatment by administering a solution 20 minutes before they wish to fall asleep. They are encouraged to observe how their body responds to the CBD and then adjust timing and doses accordingly.  

Along with taking CBD, there are simple, cost-free ways to improve your ability to have a restful night. Experts suggest avoiding caffeine (or at least limiting it later in the day), reducing exposure to light (including from electronics) at least an hour before bedtime, and keeping a consistent sleep schedule. Light stretching or reading may also aid in relaxation.

An additional article we think you will like – Tikva and Pharmacokinetic Studies.


Babson, K.A., Sottile, J., & Morabito, D. (2017). Cannabis, cannabinoids, and sleep: A review of the literature. Current Psychiatry Reports, 19(23).

Breus, M.J. (2019). How CBD can improve your sleep, mood, and health. Psychology Today.

Centers for Disease Control and Prevention. (2016). “1 in 3 adults don’t get enough sleep: A good night’s sleep is critical for good health.”

Harvard Medical School. (2017). Learn the risk of sleep aids. Harvard Health Letter.

Jung, Y. & St. Louis, E.K. (2016).  “Treatment of REM Sleep Behavior Disorder.” Current Treatment Options Neurology. 18(50). DOI 10.1007/s11940-016-0433-2

Kumar Chattu, V., et. al. (2018). “Insufficient sleep syndrome: Is it time to classify it as a major noncommunicable disease?” Sleep Science, 11, pp 56-64.

Piccirillo, J.F. (2007). Melatonin. Progress in Brain Research. 166. pp 331-333.

Rupp, T. L., Acebo, C., & Carskadon, M.A. (2007). “Evening Alcohol Suppresses Salivary Melatonin in Young Adults.” Chronobiology International. 24(3). pp 463-470. DOI: 10.1080/07420520701420675